Hosha isiriyo chirwere chechiFits Kudzora zviyero zveropa chikamu chakakosha chekutarisira kwevarwere veCKD, uye ma phosphate Binders ndiyo dombo redhorobha rekurapa kwe hyperphatema. Mumakore achangopfuura,lanthanum kabhoni, Semhando idzva risina-calcium uye isiri-aluminium phosphato binder, zvishoma nezvishoma vakapinda munda wevanhu vechiono uye vakatanga "makwikwi" neiyo tsika yedhisheni.
Iyo "Merits" uye "Dermerits" yetsika yedhishati binders
Tsika dzeSposphate Binders dzinonyanya kusanganisira binders-phosphate Binders (akadai calcium carbonate uye calcium acetate) uye aluminium-ine phosphate binders (senge aluminium hydroxide). Vanosanganisa ne phosphates mune chikafu kuti vagadzire mishonga isinganzwisisike, nekudaro ichidzikisa kukwidza kwemukati kwe phosphorus.
Calcium-ine phosphate Binders: Yakaderera Mutengo uye yakajeka phosphorus-kuderedza mhedzisiro, asi kushandiswa kwenguva refu kunogona kutungamira ku hypercalcemia uye kuwedzera njodzi yekusagadzikana.
Aluminium-ine phosphorus binders: Yakasimba phosphorus kuderedza:
Lanthanum kabhoni: Kukwira Newcomp, ine zvakakurumbira zvakanakira
Lanthanum kabhoni kabhoni kabhoni yeiyo isingawanzo nyika simbi Element Lanthanum, ine yakasarudzika phosphorus inosunga michina. Inosunungura Lanthanamu ion in the acidic nharaunda yeiyo yekugaya turakiti uye mafomu akanyanya kuisirwa lanthanum phosphate ne phosphase, nekudaro achidzivirira kuputika kwe phosphorus.
Sumo pfupi yeLanthanu carbonate
| Chigadzirwa Zita | Lanthanum kabhoni |
| Formula | LA2 (Co3) 3.XH2O |
| CAS. | 6487-39-4 |
| Sreek inoremerwa | 457.85 (Anhy) |
| Density | 2.6 g / cm3 |
| Inonyungudika | N / a |
| Chitarisiko | White Crystal Poda |
| Solubility | Nyura mumvura, zvine mwero zvine mwero mune yakasimba mineral acids |
| Kugadzikana | Nyore hygrakecopic |
Kuenzaniswa neNetsika Fosphorus Binders, Lanthanum kabhoni ine zvakabatsira:
Hapana calcium uye aluminium, yakakwirira kuchengetedza: inodzivirira njodzi yehypercalcemia uye aluminium chepfu yehupfu, kunyanya varwere vane maronda ekurapa kwenguva refu uye njodzi yekukasira.
STOPSPHORUS Sunga kugona, phosphorus kuderedza
Vashoma gastrointestinal kusagadzikana, kutevedzera kabhoni rekutsigira kwakanaka, kuri nyore kutora, kushungurudzika kushoma, uye varwere vanokwanisa kuomerera pakurapwa kwenguva refu.
Clinical Research Uchapupu: Lanthanum kabhoni Carbonate anoita zvakanaka
Zvidzidzo zvakawanda zvechiriniki zvakasimbisa kushanda uye kuchengetedzwa kwe lanthanum carbonate mune ckd varwere. Zvidzidzo zvakaratidza kuti Lanthanum kabhoni haina kuderera kune kana kunyange zvakakwirira pane zvetsika phosphate binders mukuderedza levhs Uye zvakare, kuchengetedzeka kwekurapa kwenguva refu ne lanthanum kabhoni yakanaka, uye hapana pachena lanthanum kuunganidzwa uye kuita kwepfuma kwakawanikwa.
Kurapwa kwakasiyana-siyana: Sarudza iyo yakanakisa chirongwa chemurwere
Kunyangwe mararamiro emanzwiro ane zvakawanda zvakanakira, hazvireve kuti zvinogona kutsiva zvachose tsika yechinyakare phosphate binders. Mumwe nemumwe mushonga une zviratidzo zvacho uye zvinokanganisa, uye chirongwa chekurapa chinofanira kuve chakapihwa maererano nemamiriro ezvinhu chaiwo emurwere.
Lanthanum kabhoni inokodzera kune varwere vanotevera:
Varwere vane hypercalcemia kana njodzi ye hypercalcemia
Varwere vane vascular calcification kana njodzi yekusagadzikana vascular
Varwere vane hushamwari kusimba kana kushamwaridzana kwekushanda kwetsika yechinyakare phosphate binders
Tsika yedhisheni yedhisheni inogona kuramba ichishandiswa kune varwere vanotevera:
Varwere vane mashoma ehupfumi mamiriro
Varwere vane allergic kune kana kusashivirira kwe lanthanum kabhoni
Kutarisa kune ramangwana: Lanthanum kabhoni ine ramangwana rakajeka
Nekunyepedzera kwekutsvaga kwekiriniki uye kuunganidzwa kwechiriniki chiitiko, chimiro cheLanthanum carbonate mukurapa kwe hyperphatema mune ckd varwere vacharamba vachivandudza. Mune ramangwana, Lanthanum kabhoni inotarisirwa kuve yekutanga-mutsara Phosphato Binder, kuunza nhau dzakanaka kune vamwe varwere veCKD.
Kutumira Nguva: Mar-25-2025